The Oakland A's won their seventh straight and remained tied for second place in the the AL West with the A's, five games behind Texas, after pounding the Toronto Blue Jays, 16-0, Wednesday night in Oakland.
It was Romero's shortest outing of the year and his sixth straight start in which he earned the loss.
Crisp hit solo homers in the third and fifth innings, going 3-for-6 with two RBI and three runs. The A's scored at least one run in every inning except the fourth and seventh.
Toronto remained tied with the Red Sox in last place in the AL East and will seek to avoid being swept at home when they take the field in the third game of their series with the A's, Thursday afternoon.
Jesus Guzman, who spent most of the past three years in the minors, was the main protagonist against Lincecum, singling and scoring in the fourth inning and socking a two-run homer with two down in the fifth, ending Lincecum's day on the mound.
Leading off the eighth, Guzman connected again with a solo shot, his sixth of the season. He finished 3-for-4 with three runs scored and three RBI.
The Giants were fortunate in that both Los Angeles and Arizona also lost, so they remain in first place with a 2 1/2 game lead over the Dodgers and six ahead of the Diamondbacks in the NL West.
San Francisco hosts an important three-game weekend series with the Dodgers beginning Friday.
14 games back and hopelessly out of the division and wild card races, rumors that the Padres were looking to trade third baseman Chase Headley were widely circulated.