|Sanchez: 7IP 3H 0ER|
Kuroda had been perfect through five, but Jhonny Peralta singled to open the sixth and the Tigers scored the game's first run when Delmon Young hit into a fielder's choice with one out, scoring Quentin Berry from third.
The Tigers tacked on two more with two out in the eighth, chasing Kuroda and working through four relievers in the frame.
Cardinal starter Lance Lynn didn't fare much better, working the same 3 2/3 innings, but only allowing four runs before taking an early shower.
The St. Louis and Giant bullpens were both spot on, allowing just one hit between them - Marco Sucaro's leadoff single in the fifth - from the fifth inning onward.
David Freese and Carlos Beltran each connected for two-run homers to highlight the St. Louis attack, leading to a 1-0 lead in the series, with game two scheduled for Monday night at 8:07 pm in San Francisco.